Cellular cytotoxicity and in-vivo biodistribution of docetaxel poly(lactide-co-glycolide) nanoparticles.

@article{Esmaeili2010CellularCA,
  title={Cellular cytotoxicity and in-vivo biodistribution of docetaxel poly(lactide-co-glycolide) nanoparticles.},
  author={Farnaz Esmaeili and Rassoul Dinarvand and Mohammad Hossein Ghahremani and Seyed Nasser Ostad and Hadi Esmaily and Fatemeh Atyabi},
  journal={Anti-cancer drugs},
  year={2010},
  volume={21 1},
  pages={43-52}
}
Docetaxel (DTX) is one of the most effective antineoplastic drugs. However, its current clinical administration, formulated in tween80, causes serious side effects. This study is focused on preparation and evaluation of poly(lactide-co-glycolide) nanoparticles (NPs) containing DTX to remove tween80. Drug encapsulation efficiency, in-vitro drug release… CONTINUE READING