Cellular context in epigenetics: quantitative multicolor imaging and automated per-cell analysis of miRNAs and their putative targets.

@article{Mansfield2010CellularCI,
  title={Cellular context in epigenetics: quantitative multicolor imaging and automated per-cell analysis of miRNAs and their putative targets.},
  author={James R Mansfield},
  journal={Methods},
  year={2010},
  volume={52 4},
  pages={271-80}
}
Epigenetics in general and microRNA (miRNA) in particular are an important and growing field of research, and while significant advances in the role of miRNA in a variety of diseases including cancer have been made, the majority of the information on the relationship between miRNA and its putative target proteins have been made on homogenized tissue, which, while useful, provides no information on tissue- or cell-specific signatures or relationships. Developments in spectral imaging have made… CONTINUE READING

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