Cellular composition of Corynebacterium pseudotuberculosis pyogranulomas in sheep.

  title={Cellular composition of Corynebacterium pseudotuberculosis pyogranulomas in sheep.},
  author={Michel P{\'e}pin and J C Pittet and Michel Olivier and I Gohin},
  journal={Journal of leukocyte biology},
  volume={56 5},
The cellular composition of 46 pyogranulomas experimentally induced with Corynebacterium pseudotuberculosis in sheep was determined by immunohistochemistry. Lesions localized in inoculation sites or draining lymph nodes consisted of macrophage and lymphocyte layers distributed around a necrotic center and surrounded by a fibrous capsule. In immature lesions, T cells of the CD4+ subset predominated, whereas in mature lesions proportions of CD8+ T lymphocytes and cells expressing the gamma/delta… CONTINUE READING

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