Cellular catabolism of normal very low density lipoproteins via the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor is induced by the C-terminal domain of lipoprotein lipase.

@article{Chappell1994CellularCO,
  title={Cellular catabolism of normal very low density lipoproteins via the low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor is induced by the C-terminal domain of lipoprotein lipase.},
  author={David A. Chappell and Ituro Inoue and Gareth L.A. Fry and Marc W. Pladet and Sharn L Bowen and P. H. Iverius and J. M. Lalouel and Dudley K Strickland},
  journal={The Journal of biological chemistry},
  year={1994},
  volume={269 27},
  pages={
          18001-6
        }
}
Lipoprotein lipase (LPL) binds to the low density lipoprotein receptor-related protein (LRP)/alpha 2-macroglobulin receptor and induces catabolism of normal human very low density lipoproteins (VLDL) via LRP in vitro. Recent studies showed that the C-terminal domain of LPL can bind LRP in solid phase assays and inhibit cellular catabolism of two LRP ligands, activated alpha 2-macroglobulin and the 39-kDa receptor-associated protein (Williams, S.E., Inoue, I., Tran, H., Fry, G. L., Pladet, M.W… CONTINUE READING

Citations

Publications citing this paper.
SHOWING 1-10 OF 19 CITATIONS

Serum lipoprotein lipase mass: clinical significance of its measurement.

  • Clinica chimica acta; international journal of clinical chemistry
  • 2007
VIEW 1 EXCERPT
CITES BACKGROUND

Nutritional regulation of binding sites for lipoprotein lipase in rat heart.

  • American journal of physiology. Endocrinology and metabolism
  • 2000
VIEW 1 EXCERPT
CITES BACKGROUND