Cellular basis for complex T waves and arrhythmic activity following combined I(Kr) and I(Ks) block.

@article{Emori2001CellularBF,
  title={Cellular basis for complex T waves and arrhythmic activity following combined I(Kr) and I(Ks) block.},
  author={Tetsuro Emori and Charles Antzelevitch},
  journal={Journal of cardiovascular electrophysiology},
  year={2001},
  volume={12 12},
  pages={1369-78}
}
INTRODUCTION A growing number of cardiomyopathies have been shown to result in a reduction in both I(Kr) and I(Ks) yet little is known about the electrophysiologic and ECG characteristics of combined I(Kr) and I(Ks) block. METHODS AND RESULTS To address this gap in our knowledge, transmembrane action potentials (APs) from epicardial, M, and endocardial cells were recorded simultaneously, together with a transmural ECG from arterially perfused canine left ventricular wedge preparations exposed… CONTINUE READING

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