Cellular basis for blunted volume expansion natriuresis in experimental nephrotic syndrome.

@article{Valentin1992CellularBF,
  title={Cellular basis for blunted volume expansion natriuresis in experimental nephrotic syndrome.},
  author={J. P. Valentin and Chenxia Qiu and W P Muldowney and W Z Ying and David G. Gardner and Michael H. Humphreys},
  journal={The Journal of clinical investigation},
  year={1992},
  volume={90 4},
  pages={1302-12}
}
Experimental nephrotic syndrome results in sodium retention, reflecting, at least in part, an intrinsic defect in renal sodium handling in the distal nephron. We studied the relationships among plasma atrial natriuretic peptide (ANP) concentration, sodium excretion (UNaV), and urinary cyclic GMP excretion (UcGMPV) in vivo, and the responsiveness of isolated glomeruli and inner medullary collecting duct (IMCD) cells to ANP in vitro, in rats with adriamycin nephrosis (6-7 mg/kg body weight… CONTINUE READING
26 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 26 extracted citations

Similar Papers

Loading similar papers…