Cellular and sub-cellular localisation of GABA(B1) and GABA(B2) receptor proteins in the rat cerebellum.

@article{Ige2000CellularAS,
  title={Cellular and sub-cellular localisation of GABA(B1) and GABA(B2) receptor proteins in the rat cerebellum.},
  author={Antoinette O Ige and J. Paul Bolam and Andrew Billinton and J. H. White and Fiona H Marshall and Piers C. Emson},
  journal={Brain research. Molecular brain research},
  year={2000},
  volume={83 1-2},
  pages={
          72-80
        }
}
Following the recent discovery that GABA(B) receptors expressed in cell lines are only functional when both GABA(B1) and GABA(B2) are expressed, the present study reports on the development of polyclonal antisera specific for carboxyl-terminal portions of the two related GABA(B) receptor components respectively. Western blotting indicated the specificity of affinity-purified antibodies for native or recombinant expressed GABA(BR1) and GABA(BR2), with no cross-reactivity, both antisera detecting… CONTINUE READING
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