Cellular and molecular regulation of muscle regeneration.

@article{Charg2004CellularAM,
  title={Cellular and molecular regulation of muscle regeneration.},
  author={Sophie B. P. Charg{\'e} and Michael A. Rudnicki},
  journal={Physiological reviews},
  year={2004},
  volume={84 1},
  pages={
          209-38
        }
}
Under normal circumstances, mammalian adult skeletal muscle is a stable tissue with very little turnover of nuclei. However, upon injury, skeletal muscle has the remarkable ability to initiate a rapid and extensive repair process preventing the loss of muscle mass. Skeletal muscle repair is a highly synchronized process involving the activation of various cellular responses. The initial phase of muscle repair is characterized by necrosis of the damaged tissue and activation of an inflammatory… Expand
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