Cellular and molecular mechanisms regulating fibrosis in skeletal muscle repair and disease.

@article{Serrano2011CellularAM,
  title={Cellular and molecular mechanisms regulating fibrosis in skeletal muscle repair and disease.},
  author={Antonio Serrano and Christopher J. Mann and Berta Vidal and Esther Ardite and Eusebio Perdiguero and Pura Mu{\~n}oz-C{\'a}noves},
  journal={Current topics in developmental biology},
  year={2011},
  volume={96},
  pages={167-201}
}
The repair of an injured tissue is a complex biological process involving the coordinated activities of tissue-resident and infiltrating cells in response to local and systemic signals. Following acute tissue injury, inflammatory cell infiltration and activation/proliferation of resident stem cells is the first line of defense to restore tissue homeostasis. However, in the setting of chronic tissue damage, such as in Duchenne Muscular Dystrophy, inflammatory infiltrates persist, the ability of… CONTINUE READING

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