Cellular and molecular mechanisms of dietary regulation on rat intestinal H+/Peptide transporter PepT1.

@article{Shiraga1999CellularAM,
  title={Cellular and molecular mechanisms of dietary regulation on rat intestinal H+/Peptide transporter PepT1.},
  author={T Shiraga and Ken-Ichi Miyamoto and Hiromitsu Tanaka and Hiroki Yamamoto and Yutaka Taketani and Kyoko Morita and Ikumi Tamai and Akira Tsuji and Eiji Takeda},
  journal={Gastroenterology},
  year={1999},
  volume={116 2},
  pages={354-62}
}
BACKGROUND & AIMS Dietary regulation is one of the most important factors of intestinal peptide transport. However, the cellular and molecular mechanisms of dietary regulation of the intestinal peptide transport system remain unknown. This study investigated the molecular mechanism of transcriptional activation of intestinal peptide transporter (PepT1) gene by the dietary protein. The promoter region of the rat PepT1 gene was isolated and characterized. METHODS PepT1 messenger RNA levels were… CONTINUE READING
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