Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs

@article{CunhaOliveira2008CellularAM,
  title={Cellular and molecular mechanisms involved in the neurotoxicity of opioid and psychostimulant drugs},
  author={T. Cunha-Oliveira and A. Rego and C. Oliveira},
  journal={Brain Research Reviews},
  year={2008},
  volume={58},
  pages={192-208}
}
Substance abuse and addiction are the most costly of all the neuropsychiatric disorders. In the last decades, much progress has been achieved in understanding the effects of the drugs of abuse in the brain. However, efficient treatments that prevent relapse have not been developed. Drug addiction is now considered a brain disease, because the abuse of drugs affects several brain functions. Neurological impairments observed in drug addicts may reflect drug-induced neuronal dysfunction and… Expand
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