Cellular and molecular effects of growth hormone and estrogen on human bone cells.

@article{Kassem1997CellularAM,
  title={Cellular and molecular effects of growth hormone and estrogen on human bone cells.},
  author={Moustapha S Kassem},
  journal={APMIS. Supplementum},
  year={1997},
  volume={71},
  pages={
          1-30
        }
}
The aim of the present thesis is to examine some aspects of the biological effects of growth hormone (GH) and estrogen on bone cells in vitro. The first part of the thesis describes characterization of model systems to study normal human osteoblasts and osteoclasts in vitro. Three culture systems for human osteoblasts have been characterized, representing different stages of osteoblasts differentiation/maturation: (1) mature osteoblasts cultured from trabecular bone explants (trabecular… CONTINUE READING
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