Cellular and genetic mechanisms involved in the generation of protective and pathogenic immune responses in human Chagas disease.

@article{Dutra2009CellularAG,
  title={Cellular and genetic mechanisms involved in the generation of protective and pathogenic immune responses in human Chagas disease.},
  author={Walderez O Dutra and Cristiane Alves da Silva Menezes and Fernanda Nobre Amaral Villani and Germano Carneiro da Costa and A B M da Silveira and D{\'e}bora d'{\'A}vila Reis and K J Gollob},
  journal={Memorias do Instituto Oswaldo Cruz},
  year={2009},
  volume={104 Suppl 1},
  pages={208-18}
}
Perhaps one of the most intriguing aspects of human Chagas disease is the complex network of events that underlie the generation of protective versus pathogenic immune responses during the chronic phase of the disease. While most individuals do not develop patent disease, a large percentage may develop severe forms that eventually lead to death. Although many efforts have been devoted to deciphering these mechanisms, there is still much to be learned before we can fully understand the… CONTINUE READING
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