Cellular and Molecular Mechanisms of Autoimmunity and Lupus Nephritis.


Autoimmunity involves immune responses directed against self, which are a result of defective self/foreign distinction of the immune system, leading to proliferation of self-reactive lymphocytes, and is characterized by systemic, as well as tissue-specific, inflammation. Numerous mechanisms operate to ensure the immune tolerance to self-antigens. However… (More)
DOI: 10.1016/bs.ircmb.2016.12.001