Cellular and Molecular Mechanisms of Arrhythmia by Oxidative Stress

@inproceedings{Sovari2016CellularAM,
  title={Cellular and Molecular Mechanisms of Arrhythmia by Oxidative Stress},
  author={Ali Alizadeh Sovari},
  booktitle={Cardiology research and practice},
  year={2016}
}
Current therapies for arrhythmia using ion channel blockade, catheter ablation, or an implantable cardioverter defibrillator have limitations, and it is important to search for new antiarrhythmic therapeutic targets. Both atrial fibrillation and heart failure, a condition with increased arrhythmic risk, are associated with excess amount of reactive oxygen species (ROS). There are several possible ways for ROS to induce arrhythmia. ROS can cause focal activity and reentry. ROS alter multiple… CONTINUE READING