Cellular and Molecular Mechanisms in the Two Major Forms of Inflammatory Bowel Disease

@article{Bene2011CellularAM,
  title={Cellular and Molecular Mechanisms in the Two Major Forms of Inflammatory Bowel Disease},
  author={L{\'a}szl{\'o} Bene and Andr{\'a}s Falus and Noemi J. Baffy and Andras Kristof Fulop},
  journal={Pathology & Oncology Research},
  year={2011},
  volume={17},
  pages={463-472}
}
The factors involved in the pathogenesis of Crohn’s disease and ulcerative colitis, the two major types of inflammatory bowel disease (IBD) are summarized. Intestinal antigens composed of bacterial flora along with antigen presentation and impaired mucosal barrier have an important role in the initiation of IBD. The bacterial community may be modified by the use of antibiotics and probiotics. The dentritic cells recognize the antigens by cell surface Toll like receptor and the cytoplasmic CARD… CONTINUE READING
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