Cellular and Molecular Mechanisms in the Two Major Forms of Inflammatory Bowel Disease

  title={Cellular and Molecular Mechanisms in the Two Major Forms of Inflammatory Bowel Disease},
  author={L{\'a}szl{\'o} Bene and Andr{\'a}s Falus and Noemi J. Baffy and Andras Kristof Fulop},
  journal={Pathology & Oncology Research},
The factors involved in the pathogenesis of Crohn’s disease and ulcerative colitis, the two major types of inflammatory bowel disease (IBD) are summarized. Intestinal antigens composed of bacterial flora along with antigen presentation and impaired mucosal barrier have an important role in the initiation of IBD. The bacterial community may be modified by the use of antibiotics and probiotics. The dentritic cells recognize the antigens by cell surface Toll like receptor and the cytoplasmic CARD… CONTINUE READING
Highly Cited
This paper has 30 citations. REVIEW CITATIONS


Publications citing this paper.
Showing 1-10 of 13 extracted citations


Publications referenced by this paper.
Showing 1-10 of 86 references

Differences Between Ulcerative Colitis and Crohn’s Disease

AJ Tresca
In: About.com: Health. http://ibdcrohns.about. com/od/ulcerativecolitis/a/diffuccd.htm. Cited • 2009
View 1 Excerpt

Hungarian IBD Study Group et al (2009) The 3′UTR NFKBIA variant is associated with extensive colitis in Hungarian IBD patients

T Szamosi, PL Lakatos
Dig Dis Sci • 2009
View 1 Excerpt