Cellular and Genetic Analysis of Wound Healing in Drosophila Larvae

@article{Galko2004CellularAG,
  title={Cellular and Genetic Analysis of Wound Healing in Drosophila Larvae},
  author={Michael J. Galko and Mark A Krasnow},
  journal={PLoS Biology},
  year={2004},
  volume={2},
  pages={2322 - 2329}
}
To establish a genetic system to study postembryonic wound healing, we characterized epidermal wound healing in Drosophila larvae. Following puncture wounding, larvae begin to bleed but within an hour a plug forms in the wound gap. Over the next couple of hours the outer part of the plug melanizes to form a scab, and epidermal cells surrounding the plug orient toward it and then fuse to form a syncytium. Subsequently, more-peripheral cells orient toward and fuse with the central syncytium… CONTINUE READING

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