Cellular acidosis in rodents exposed to cadmium is caused by adaptation of the tissue rather than an early effect of toxicity.

@article{Jones2007CellularAI,
  title={Cellular acidosis in rodents exposed to cadmium is caused by adaptation of the tissue rather than an early effect of toxicity.},
  author={Oliver A H Jones and Lee A Walker and Jeremy K. Nicholson and R F Shore and Julian Leether Griffin},
  journal={Comparative biochemistry and physiology. Part D, Genomics & proteomics},
  year={2007},
  volume={2 4},
  pages={316-21}
}
Proton ((1)H) Nuclear Magnetic Resonance (NMR) spectroscopy was used to investigate the biochemical response of bank voles and wood mice (two wild rodent species frequently found on metal-contaminated sites) to chronic cadmium (Cd) insult. Similar effects, in terms of both metabolic changes (consistent with cellular acidosis) and induced metallothionin (MT) production were observed in all animals. These changes appeared to be an adaptation of the liver to toxic insult rather than onset of a… CONTINUE READING

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