Corpus ID: 236428810

Cellular Sensing Governs the Stability of Chemotactic Fronts

  title={Cellular Sensing Governs the Stability of Chemotactic Fronts},
  author={Ricard Alert and Sujit S. Datta},
In contexts ranging from embryonic development to bacterial ecology, cell populations migrate chemotactically along self-generated chemical gradients, often forming a propagating front. Here, we theoretically show that the stability of such chemotactic fronts to morphological perturbations is determined by limitations in the ability of individual cells to sense and thereby respond to the chemical gradient. Specifically, cells at bulging parts of a front are exposed to a smaller gradient, which… Expand
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