Cellular Senescence Markers p16INK4a and p21CIP1/WAF Are Predictors of Hodgkin Lymphoma Outcome.

Abstract

PURPOSE There is evidence that Hodgkin Reed-Sternberg (HRS) cells in classical Hodgkin lymphoma (cHL) could display some molecular and morphologic markers of cellular senescence (CS). We hypothesized that CS mechanisms may have potential prognostic relevance in cHL and investigated whether the expression of the well-established CS biomarkers p21(CIP1/WAF1… (More)
DOI: 10.1158/1078-0432.CCR-15-0508

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Cite this paper

@article{Cali2015CellularSM, title={Cellular Senescence Markers p16INK4a and p21CIP1/WAF Are Predictors of Hodgkin Lymphoma Outcome.}, author={Anna Cali{\`o} and Alberto Zam{\`o} and Maurilio Ponzoni and M Elisabetta Zanolin and Andr{\'e}s J M Ferreri and Serena Pedron and Licia Montagna and C. Parolini and Vadim E. Fraifeld and Marina Wolfson and Hagai Yanai and Giovanni Pizzolo and Claudio Doglioni and Fabrizio Vinante and Marco Chilosi}, journal={Clinical cancer research : an official journal of the American Association for Cancer Research}, year={2015}, volume={21 22}, pages={5164-72} }