Cellular Prion Protein Promotes Neuronal Differentiation of Adipose-Derived Stem Cells by Upregulating miRNA-124

Abstract

The cellular prion protein (PrPC) is a highly conserved glycoprotein anchored by glycosylphosphatidylinositol (GPI) to the cell surface and is also the source of pathogenic agent of scrapie prion protein (PrPSc). Numerous researches have suggested putative physiological roles for PrPC, including protection from ischemic and excitotoxic lesions, and… (More)
DOI: 10.1007/s12031-016-0733-8

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