Cellular Immunotherapy — Towards Direct DC Activation for Licence to Kill

@inproceedings{Ossendorp2003CellularI,
  title={Cellular Immunotherapy — Towards Direct DC Activation for Licence to Kill},
  author={Ferry A. Ossendorp and Sh Van Der Burg and Ren{\'e} E. M. Toes and Rienk Offringa and Cornelis J M Melief},
  year={2003}
}
In the case of cancer immunity, specific T cells against tumor associated antigens have been shown to be effective. In a bone marrow transplantation setting, adoptive transfer of Epstein Bar virus-specific T cells or infusion of donor lymphocytes, following relapse of chronic myelogenous leukemia, have proven their therapeutic potential. Theoretically, adoptive transfer therapy with highly purified and large quantities of specific CD8+ cytotoxic T lymphocytes (CTL) is desirable for many cancer… CONTINUE READING