Cells of the oligodendrocyte lineage proliferate following cortical stab wounds: an in vitro analysis.

@article{Amat1998CellsOT,
  title={Cells of the oligodendrocyte lineage proliferate following cortical stab wounds: an in vitro analysis.},
  author={Jose A Amat and Muhammad Farooq and Hiroshi Ishiguro and William T. Norton},
  journal={Glia},
  year={1998},
  volume={22 1},
  pages={64-71}
}
We have previously shown that a cortical stab wound induces the proliferation of microglia and astrocytes in situ, but no evidence was obtained for proliferation of cells of the oligodendrocyte lineage (Amat et al., 1996). To study further the properties of cells involved in repair following brain injury, groups of adult rats received either sham operations or bilateral stab wounds. Proliferating cells were labeled in vivo 3 days later with [3H]-thymidine (Thy) and sacrificed the same day… CONTINUE READING
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