Cells of renin lineage express hypoxia inducible factor 2α following experimental ureteral obstruction

@inproceedings{Stefaska2016CellsOR,
  title={Cells of renin lineage express hypoxia inducible factor 2α following experimental ureteral obstruction},
  author={Ania Stefańska and Diana G. Eng and Natalya V. Kaverina and Jeffrey W. Pippin and Kenneth W. Gross and Jeremy S. Duffield and Stuart J. Shankland},
  booktitle={BMC nephrology},
  year={2016}
}
BACKGROUND Recent studies indicate that mural cells of the preglomerular vessels, known as cells of renin lineage (CoRL), contribute to repair and regeneration of injured kidney glomeruli. However, their potential roles in tubulointerstitial disease are less understood. The aim of this study was to better understand CoRL number and distribution following UUO so that future mechanistic studies could be undertaken. METHODS We mapped the fate of CoRL in adult Ren1cCreER x Rs-tdTomato-R reporter… CONTINUE READING
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