Cells of adult brain germinal zone have properties akin to hair cells and can be used to replace inner ear sensory cells after damage.

Abstract

Auditory hair cell defect is a major cause of hearing impairment, often leading to spiral ganglia neuron (SGN) degeneration. The cell loss that follows is irreversible in mammals, because inner ear hair cells (HCs) have a limited capacity to regenerate. Here, we report that in the adult brain of both rodents and humans, the ependymal layer of the lateral… (More)
DOI: 10.1073/pnas.0808044105

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