Cells isolated from the human cortical interstitium resemble myofibroblasts and bind neutrophils in an ICAM-1--dependent manner.

@article{Clayton1997CellsIF,
  title={Cells isolated from the human cortical interstitium resemble myofibroblasts and bind neutrophils in an ICAM-1--dependent manner.},
  author={Amy E Clayton and Robert Steadman and John David Williams},
  journal={Journal of the American Society of Nephrology : JASN},
  year={1997},
  volume={8 4},
  pages={604-15}
}
Progressive renal disease is frequently accompanied by renal interstitial inflammation and fibrosis in which the activity of resident fibroblasts may be of central importance. Because there are relatively few fibroblasts in the normal cortical interstitium and there is no specific marker to permit their identification, these cells have proved difficult to characterize in vitro. In this study, these cells were isolated and established in culture, using CD90 as a positive selection marker… CONTINUE READING
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