Cells infected with herpes simplex virus induce human monocyte-macrophages to produce interferon.

Abstract

Human monocyte-macrophages (MO) produced interferon when incubated with human fibroblast, Vero cell, or rabbit kidney cell cultures infected with herpes simplex virus (HSV). Induction of MO interferon required a 12-hour incubation with the HSV-infected cultures. The interferon produced biologically resembled human leukocyte-derived rather than human fibroblasts-derived interferon.

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@article{Stanwick1981CellsIW, title={Cells infected with herpes simplex virus induce human monocyte-macrophages to produce interferon.}, author={T. L. Stanwick and Duncan E Campbell and Andre Joseph Nahmias}, journal={Immunobiology}, year={1981}, volume={158 3}, pages={207-12} }