Cells derived from the circulation contribute to the repair of lung injury.

@article{Abe2004CellsDF,
  title={Cells derived from the circulation contribute to the repair of lung injury.},
  author={Shinji Abe and Craig W. Boyer and Xiangde D Liu and Fu Qiang Wen and Tetsu Kobayashi and Qiuhong H Fang and Xingqi Wang and Mitsuyoshi Hashimoto and John Graham Sharp and Stephen I. Rennard},
  journal={American journal of respiratory and critical care medicine},
  year={2004},
  volume={170 11},
  pages={1158-63}
}
Bone marrow (stem/progenitor) cells have been shown to "differentiate" into cells in multiple tissues, including lung. A low number of hematopoietic stem/progenitor cells also circulate in peripheral blood. The physiologic roles of these cells are still uncertain. This study was designed to test, using parabiotic mice that were joined surgically, whether stem/progenitor cells in blood contributed to the regeneration of lung after injury. Parabiotic mice were generated surgically by joining… CONTINUE READING
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