Cells Stimulate Migratory and Cytolytic Activity of Natural Killer Heat Shock Protein 70 Surface-Positive Tumor Exosomes

@inproceedings{Gastpar2005CellsSM,
  title={Cells Stimulate Migratory and Cytolytic Activity of Natural Killer Heat Shock Protein 70 Surface-Positive Tumor Exosomes},
  author={Robert Gastpar and Mathias Gehrmann and Mar{\'i}a A. Bausero and Alexzander Asea and Catharina Gross and Josef A. Schroeder and Gabriele Multhoff},
  year={2005}
}
Detergent-soluble membrane vesicles are actively released by human pancreas (Colo /Colo+) and colon (CX /CX+) carcinoma sublines, differing in their capacity to present heat shock protein 70 (Hsp70)/Bag-4 on their plasma membranes. Floating properties, acetylcholine esterase activity, and protein composition characterized them as exosomes. An enrichment of… CONTINUE READING