Cells Inhibitor of Estrogen Receptor-negative Human Breast Cancer : Potential Autocrine Growth β Transforming Growth Factor

@inproceedings{Arteaga1988CellsIO,
  title={Cells Inhibitor of Estrogen Receptor-negative Human Breast Cancer : Potential Autocrine Growth β Transforming Growth Factor},
  author={Carlos L. Arteaga and Atul K. Tandon and Daniel Von Hoff and Charles Osborne},
  year={1988}
}
Transforming growth factor ß(TGF0), a two-subunit M, 25,000 poh peptide, inhibits growth of several epithelial human cancer cell lines and has been proposed as an autocrine growth inhibitor. IGF/3 activity has been found in conditioned media from some breast cancer cell lines, and TGF/3 niR.NA has been detected in breast cancer cell lines and human breast cancer specimens. In the present study we attempted to character ize the interaction of TGF/S with breast cancer cells by examining the… CONTINUE READING

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