CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging

Abstract

Fluorescence time-lapse imaging has become a powerful tool to investigate complex dynamic processes such as cell division or intracellular trafficking. Automated microscopes generate time-resolved imaging data at high throughput, yet tools for quantification of large-scale movie data are largely missing. Here we present CellCognition, a computational… (More)
DOI: 10.1038/nmeth.1486