Cell wall synthesis is a major target of mycoparasitic antagonism by Trichoderma harzianum.

  title={Cell wall synthesis is a major target of mycoparasitic antagonism by Trichoderma harzianum.},
  author={Matteo Lorito and Vladim{\'i}r Farka{\vs} and Sylvie Rebuffat and Bernard Bodo and Christian Peter Kubicek},
  journal={Journal of bacteriology},
  volume={178 21},
We have investigated the molecular basis for the reported synergism between peptaibols and cell wall hydrolytic enzymes in the antagonism of phytopathogenic fungi by Trichoderma harzianum. beta-Glucan synthase activity on isolated plasma membranes of Botrytis cinerea was inhibited in vitro by the peptaibols trichorzianin TA and TB, and this inhibition was reversed by the addition of phosphatidylcholine. beta-Glucan synthesis in vivo, assayed by the incorporation of [2-(3)H]glucose into cell… CONTINUE READING

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