Cell wall core galactofuran synthesis is essential for growth of mycobacteria.

@article{Pan2001CellWC,
  title={Cell wall core galactofuran synthesis is essential for growth of mycobacteria.},
  author={Fei Pan and Mary Jackson and Yufang Ma and Michael C McNeil},
  journal={Journal of bacteriology},
  year={2001},
  volume={183 13},
  pages={
          3991-8
        }
}
The mycobacterial cell wall core consists of an outer lipid (mycolic acid) layer attached to peptidoglycan via a galactofuranosyl-containing polysaccharide, arabinogalactan. This structural arrangement strongly suggests that galactofuranosyl residues are essential for the growth and viability of mycobacteria. Galactofuranosyl residues are formed in nature by a ring contraction of UDP-galactopyranose to UDP-galactofuranose catalyzed by the enzyme UDP-galactopyranose mutase (Glf). In… CONTINUE READING

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