Cell volume regulation in epithelial physiology and cancer

  title={Cell volume regulation in epithelial physiology and cancer},
  author={Stine Falsig Pedersen and Else Kay Hoffmann and Ivana Novak},
  booktitle={Front. Physiol.},
The physiological function of epithelia is transport of ions, nutrients, and fluid either in secretory or absorptive direction. All of these processes are closely related to cell volume changes, which are thus an integrated part of epithelial function. Transepithelial transport and cell volume regulation both rely on the spatially and temporally coordinated function of ion channels and transporters. In healthy epithelia, specific ion channels/transporters localize to the luminal and basolateral… CONTINUE READING
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