Cell viability score (CVS) as a good indicator of critical concentration of benzalkonium chloride for toxicity in cultured ocular surface cell lines.

Abstract

Cytotoxicity of benzalkonium chloride (BAK) is a major factor affecting drug cytotoxicity. This study aimed to determine the critical concentration of BAK for cultured ocular cells, using SIRC (rabbit corneal epithelium), BCE C/D-1b (bovine corneal epithelial cells), RC-1 (rabbit corneal epithelium), and Chang (human conjunctival cells). Cell viability was… (More)
DOI: 10.1016/j.yrtph.2013.03.014

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@article{Iwasawa2013CellVS, title={Cell viability score (CVS) as a good indicator of critical concentration of benzalkonium chloride for toxicity in cultured ocular surface cell lines.}, author={Atsuo Iwasawa and Masahiko Ayaki and Yoshimi Niwano}, journal={Regulatory toxicology and pharmacology : RTP}, year={2013}, volume={66 2}, pages={177-83} }