Cell viability improves following inhibition of cryopreservation-induced apoptosis

  title={Cell viability improves following inhibition of cryopreservation-induced apoptosis},
  author={John M Baust and Robert G. van Buskirk and John G. Baust},
  journal={In Vitro Cellular & Developmental Biology - Animal},
A new concept in cryopreservation solution design was developed that focuses on the use of an intracellular-type, hypothermic maintenance medium coupled with additives that inhibit cryopreservation-induced apoptosis. Hypo-Thermosol® (HTS), a hypothermic (4° C) maintenance medium utilized in the long-term storage of cell, tissue, and organ systems, was tested for cryoprotective capability on a renal cell line (Madin-Darby Canine Kidney cells). HTS and HTS derivatives were tested against… CONTINUE READING
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Caspeses: enemies within

  • N. A. Thornberry, Y. Lazenbnik
  • Science 281:
  • 1998

The effects of freezing on cell viability and mechanisms of cell death in an in vitro human prostate cancer cell line

  • W. R. Hollistcr, A. J. Mathew, G Baust.J.
  • Moh Uroh
  • 1998

Cryopreservation of multi-cellular mnbryos and reproductive tissues

  • S. Payntm, A. Coopm, Thomas, el ah
  • 1997

Fundamental myobiology of mammalian spermatozoa

  • D. Y. Gao, P. Mazur, J. K. Critser
  • 1997
1 Excerpt

Hypothermia aml mammalian gametes

  • J. E. Parks
  • 1997

Optimization of HypoThermosoF for the hypothermic storage of cardiomyocytes - - Addition of EDTA

  • A. Mathew, J. G. Baust, R. G. Van Buskirk
  • In Vitro rlbxicol .
  • 1997

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