Cell viability assessment using the Alamar blue assay: a comparison of 2D and 3D cell culture models.


Comparisons of 2D and 3D cell culture models in literature have indicated differences in cellular morphology and metabolism, commonly attributed the better representation of in vivo conditions of the latter cell culture environment. Thus, interest in the use of 3D collagen gels for in vitro analysis has been growing. Although comparative studies to date… (More)
DOI: 10.1016/j.tiv.2014.09.014


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