Cell type specificity of neurovascular coupling in cerebral cortex

  title={Cell type specificity of neurovascular coupling in cerebral cortex},
  author={Hana Uhlirova and Kıvılcım Kılıç and Peifang A. Tian and Martin Thunemann and Mich{\`e}le Desjardins and Payam A. Saisan and Sava Sakadzic and Torbj\orn V. Ness and Celine Mateo and Qun Cheng and Kimberly L Weldy and Florence Razoux and Matthieu Vandenberghe and Jonathan A Cremonesi and Christopher G. L. Ferri and Krystal Nizar and Vishnu B. Sridhar and Tyler Steed and Maxim Abashin and Yeshaiahu Fainman and Eliezer Masliah and Srdjan Djurovic and Ole A. Andreassen and Gabriel F. A. Silva and David A. Boas and David Kleinfeld and Richard B. Buxton and Gaute T. Einevoll and Anders M. Dale and Anna Devor},
Identification of the cellular players and molecular messengers that communicate neuronal activity to the vasculature driving cerebral hemodynamics is important for (1) the basic understanding of cerebrovascular regulation and (2) interpretation of functional Magnetic Resonance Imaging (fMRI) signals. Using a combination of optogenetic stimulation and 2-photon imaging in mice, we demonstrate that selective activation of cortical excitation and inhibition elicits distinct vascular responses and… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 19 times over the past 90 days. VIEW TWEETS