Cell type-specific termination of transcription by transposable element sequences

@inproceedings{Conley2012CellTT,
  title={Cell type-specific termination of transcription by transposable element sequences},
  author={Andrew B. Conley and I. King Jordan},
  booktitle={Mobile DNA},
  year={2012}
}
BackgroundTransposable elements (TEs) encode sequences necessary for their own transposition, including signals required for the termination of transcription. TE sequences within the introns of human genes show an antisense orientation bias, which has been proposed to reflect selection against TE sequences in the sense orientation owing to their ability to terminate the transcription of host gene transcripts. While there is evidence in support of this model for some elements, the extent to… CONTINUE READING
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