Cell-type-specific modulation of targets and distractors by dopamine D1 receptors in primate prefrontal cortex

@inproceedings{Jacob2016CelltypespecificMO,
  title={Cell-type-specific modulation of targets and distractors by dopamine D1 receptors in primate prefrontal cortex},
  author={Simon Nikolas Jacob and Maximilian Stalter and Andreas Nieder},
  booktitle={Nature communications},
  year={2016}
}
The prefrontal cortex (PFC) is crucial for maintaining relevant information in working memory and resisting interference. PFC neurons are strongly regulated by dopamine, but it is unknown whether dopamine receptors are involved in protecting target memories from distracting stimuli. We investigated the prefrontal circuit dynamics and dopaminergic modulation of targets and distractors in monkeys trained to ignore interfering stimuli in a delayed-match-to-numerosity task. We found that dopamine… CONTINUE READING

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The authors declare no competing financial interests

D. M. Green, J. A. Signal Detection Theory Swets, +7 authors wrote the paper. Additional information Competing financ interests
Reprints and permission information is available online at http://npg.nature.com/ reprintsandpermissions/ How to cite this article: Jacob, S. N. et al. Cell-type-specific modulation of targets and distractors by dopamine D1 receptors in primate prefrontal cortex. Nat. Commun. 7, 13218 doi: 10.1038/n • 2016

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