Cell type-specific alterations in the nucleus accumbens by repeated exposures to cocaine.

@article{Kim2011CellTA,
  title={Cell type-specific alterations in the nucleus accumbens by repeated exposures to cocaine.},
  author={Juhyun Kim and Bong-Hyun Park and Joo Han Lee and Sang Ki Park and Joung-Hun Kim},
  journal={Biological psychiatry},
  year={2011},
  volume={69 11},
  pages={1026-34}
}
BACKGROUND The nucleus accumbens (NAc) is a brain region critically involved in psychostimulant-induced neuroadaptations. A major proportion of NAc neurons consists of medium spiny neurons (MSNs), commonly divided into two major subsets on the basis of their expression of D1 dopamine receptors (D1R-MSNs) or D2 dopamine receptors (D2R-MSNs). Although NAc MSNs are known to undergo extensive alterations in their characteristics upon exposure to drugs of abuse, the functional and structural changes… CONTINUE READING

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