Cell type regulation in response to expression of ricin A in Dictyostelium.

@article{Shaulsky1993CellTR,
  title={Cell type regulation in response to expression of ricin A in Dictyostelium.},
  author={Gad Shaulsky and William F. Loomis},
  journal={Developmental biology},
  year={1993},
  volume={160 1},
  pages={85-98}
}
Expression of ricin A in either prespore or prestalk cells of Dictyostelium discoideum results in cell-autonomous lethality. Strains expressing the toxic gene under the control of a prestalk-specific regulatory region fail to culminate or form stalks, but form spores normally. Strains expressing ricin A under the control of a prespore-specific regulatory region form neither spores nor stalks. Regulation of the cell types results in conversion of prestalk cells to prespore cells when the… CONTINUE READING