Cell type dependent morphological adaptation in polyelectrolyte hydrogels governs chondrogenic fate.


Repair of critical-size articular cartilage defects typically involves delivery of cells in biodegradable, 3D matrices. Differences in the developmental status of mesenchymal stem cells (MSCs) and terminally differentiated mature chondrocytes might be a critical factor in engineering appropriate 3D matrices for articular cartilage tissue engineering. This… (More)
DOI: 10.1088/1748-6041/11/2/025013