Cell-type-Specific Labeling of Synapses In Vivo through Synaptic Tagging with Recombination

  title={Cell-type-Specific Labeling of Synapses In Vivo through Synaptic Tagging with Recombination},
  author={Yi Chen and Orkun Akin and Aljoscha Nern and C. Y. Kimberly Tsui and Matthew Y Pecot and S Lawrence Zipursky},
The study of synaptic specificity and plasticity in the CNS is limited by the inability to efficiently visualize synapses in identified neurons using light microscopy. Here, we describe synaptic tagging with recombination (STaR), a method for labeling endogenous presynaptic and postsynaptic proteins in a cell-type-specific fashion. We modified genomic loci encoding synaptic proteins within bacterial artificial chromosomes such that these proteins, expressed at endogenous levels and with normal… CONTINUE READING
Highly Influential
This paper has highly influenced 10 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS
Recent Discussions
This paper has been referenced on Twitter 4 times over the past 90 days. VIEW TWEETS
34 Citations
65 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 34 extracted citations


Publications referenced by this paper.
Showing 1-10 of 65 references

Similar Papers

Loading similar papers…