Cell traction models for generating pattern and form in morphogenesis.

@article{Murray1984CellTM,
  title={Cell traction models for generating pattern and form in morphogenesis.},
  author={James D. Murray and George F. Oster},
  journal={Journal of mathematical biology},
  year={1984},
  volume={19 3},
  pages={
          265-79
        }
}
During early development migratory mesenchymal cells navigate to distant sites where they aggregate to form a variety of embryonic organ rudiments. We present here a new model for mesenchymal cell morphogenesis based on the mechanical interaction between motile cells and their extracellular environment. The model is based on two properties of motile cells: (a) they are capable of generating large traction forces which can deform the extracellular matrix through which they move, and (b) the… CONTINUE READING
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