Cell-to-cell transmission of viruses.

  title={Cell-to-cell transmission of viruses.},
  author={Peng Zhong and Luis M. Agosto and James B. Munro and Walther Mothes},
  journal={Current opinion in virology},
  volume={3 1},
The life cycle of most viruses involves the release of particles into the extracellular space. Consequently, the study of virus egress as well as virus entry has focused almost exclusively on the biology of cell-free virus. However, cell-free virus spread is often very inefficient. Specific barriers, either located in the donor cell or in the target cell, prevent efficient spread by the cell-free mode. In contrast, viral spread by direct cell-cell contact is largely unaffected by most of these… CONTINUE READING

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