Cell-to-cell transfer of glycosylphosphatidylinositol-anchored membrane proteins during sperm maturation.

Abstract

In spermatozoa, as in other eukaryotic cells, integral membrane proteins may be anchored by a hydrophobic protein domain, or by a glycosylphosphatidylinositol (GPI) lipid anchor. Contrary to the current understanding of sperm membrane biogenesis, recent evidence shows that some of the GPI-anchored proteins are not synthesized by the spermatozoa themselves… (More)

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