Cell therapy of peripheral arterial disease: from experimental findings to clinical trials.

@article{Raval2013CellTO,
  title={Cell therapy of peripheral arterial disease: from experimental findings to clinical trials.},
  author={Zankhana Raval and Douglas W. Losordo},
  journal={Circulation research},
  year={2013},
  volume={112 9},
  pages={1288-302}
}
The age-adjusted prevalence of peripheral arterial disease in the US population was estimated to approach 12% in 1985, and as the population ages, the overall population having peripheral arterial disease is predicted to rise. The clinical consequences of occlusive peripheral arterial disease include intermittent claudication, that is, pain with walking, and critical limb ischemia (CLI), which includes pain at rest and loss of tissue integrity in the distal limbs, which may ultimately lead to… CONTINUE READING
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Intraarterial administration of bone marrow mononuclear cells in patients with critical limb ischemia : a randomized - start , placebo - controlled pilot trial ( PROVASA )

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