Cell surface tissue transglutaminase is involved in adhesion and migration of monocytic cells on fibronectin.

@article{Akimov2001CellST,
  title={Cell surface tissue transglutaminase is involved in adhesion and migration of monocytic cells on fibronectin.},
  author={Sergey Akimov and Alexey M. Belkin},
  journal={Blood},
  year={2001},
  volume={98 5},
  pages={
          1567-76
        }
}
Expression of tissue transglutaminase (transglutaminase II, tTG) was shown to increase drastically during monocyte differentiation into macrophages; however, its role in monocytic cells remains largely unknown. This study describes a novel function of cell surface tTG as an adhesion and migration receptor for fibronectin (Fn). Two structurally related transglutaminases, tTG and the A subunit of factor XIII (FXIIIA), are expressed on the surface of monocytic cells, whereas only surface tTG is… 
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