Cell surface endothelial proteins altered in experimental allergic encephalomyelitis.

@article{Sternberger1989CellSE,
  title={Cell surface endothelial proteins altered in experimental allergic encephalomyelitis.},
  author={Nancy H. Sternberger and Ludwig A. Sternberger and Marian W. Kies and C R Shear},
  journal={Journal of neuroimmunology},
  year={1989},
  volume={21 2-3},
  pages={241-8}
}
Endothelial cells (EC) are increasingly being considered as important participants in the early evolution of inflammatory and immune responses in experimental allergic encephalomyelitis (EAE). We have found that a mouse monoclonal antibody, which reacts with the luminal plasma membrane of central nervous system endothelium, detects an alteration in the blood-brain barrier (BBB) in lesions in Lewis rats with EAE. Anti-endothelial barrier antigen (EBA) reacted with microvessels in normal rat… CONTINUE READING

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